A Welcome from the Chairman

 

Dear Colleagues,

 

The Fourth International Conference on Bio-Inspired Computing: Theories and Applications will be held in Peking University. On behalf of the Organizing Committee, it is my great pleasure to welcome everyone to join our BIC-TA 2009.

 

Bio-Inspired Computing is a brand in new field. Different from the existing electronic computer, it is based on the characteristics of biology material such as DNA, membrane and nerve cell. At present, this field is becoming a research focus all over the world with the booming of biological science.

 

Since 2006, the BIC-TA is one of the flagship conferences of bio-computing. It brings together the world's leading scientists of this exciting area. Recent advances will be presented, thereby facilitating scientific idea exchange and predicting future trends. BIC-TA 2009 aims to provide a high-level international forum for researchers to present their latest results and exchange ideas. The conference has been able to attract distinguished speakers. This year we are fortunate to have Prof. Luca Cardelli, Prof. Fumiaki Tanaka, Prof. Junying Zhang and Prof. Zhigong Wang. Besides, about 80 papers are to be accepted. I¡¯m sure that we will have lively discussions.

 

The success of this conference depends on generous contributions from a large number of people and organizations. I wish to express my thanks to:

l  IEEE Beijing Section

l  National Natural Science Foundation of China

l  International Association for Mathematics and Computers in Simulation

l  Huazhong University of Science and Technology, Wuhan, China

l  Dalian University , Dalian, China

l  Zhengzhou University of Light Industry, Zhengzhou, China

I also acknowledge many individuals who spent their time and energy to make the BIC-TA 2009 a great success.

 

Finally, I wish the conference a complete success!

 

Sincerely yours,

Prof. Fuqing Yang

Conference Chairman, BIC-TA 2009

 

Program

 

FRIDAY 16 October 2009

17:00 - 20:00

City tour and drinks at Leisure City International Hotel

 

 

 

SATURDAY 17 October 2009

Master of ceremonies: Prof. Fuqing Yang

8:30 - 9:15

Registration

9:15 - 9:30

Opening

 

Invited presentation

9:30 - 10:30

Molecules as Automata
Luca Cardelli

Substantially Causative Factor Discovery for SNP Association Study based on Association Stability

Junying (Joanna) Zhang

10:30 - 10:40

Morning tea

10:40 - 11:40

DNA as a versatile programming language for nano-engineering

Fumiaki Tanaka

 

Microelectronics-Embedded Channel Bridging and Signal Regeneration of Injured Spinal Cords or among Neuron Assemble

Prof. Zhi-Gong Wang

 

Oral presentations

Session 1(DNA Computing)

Session chair: Prof Cui Guangzhao

13:30-14:00

A DNA-based supercomputing for privilege query in hybrid role hierarchy

Guan Rong

14:05- 14:35

Deterministic Algorithm for the Reordering Problem Using Tile Assembly

Yufang Huang

14:40 - 15:00

Afternoon tea

15:00 - 15:30

Implementation of the 0-1 Multi-objective Knapsack Problem Using Self-assembly of DNA Tiles

Zhen Cheng

15:35 - 16:05

A molecular computing model for 3-coloring graph problem based on circular DNA branch migration

Zhang Cheng

16:10 - 16:40

Bio-inspired Self-Organization for Supporting Dynamic Reconfiguration of Modular Agents

Kiwon Yeom

16:40 - 17:40

Student colloquium

Session 2(Evolutionary Computing)

Session chair: Prof Gao Lin and Prof Huo Hongwei

13:30 - 14:00

A Hybrid Evolutionary Algorithm for Multiobjective Optimization  

Chang Wook Ahn

14:05 - 14:35

A Novel Cooperative Bacterial Foraging Algorithm

Yichuan Shao

14:40 - 15:00

Afternoon tea

15:00 - 15:30

Combining Genetic Algorithms with Optimality

Criteria Method for Topology Optimization  

Zhimin Chen

15:35 - 16:05

An Exploratory Study of Sorting Particle Swarm Optimizer for Multiobjective Optimization     

ZHENG Bing

16:10 - 16:40

Multi-Criteria Evaluation Model Reveals SMC4L1 Gene Maybe a Breast Cancer Susceptibility Gene

Chao Xu

16:40 - 17:40

Student colloquium

Session 3(Membrane Computing and others)

Session chair: Prof Linqiang Pan

13:30 - 14:00

A Quantum-Inspired Evolutionary Algorithm Based on P systems for Radar Emitter Signals

Chunxiu Liu

14:05 - 14:35

Solving Satisfiability Problems with Membrane Algorithms

Gexiang Zhang

14:40 - 15:00

Afternoon tea

15:00 - 15:30

Solving 3-Coloring Problem by Tissue P Systems with Cell Separation

Shuo Wang

15:35 - 16:05

Obtaining Homology Groups in Binary 2D Images Using P Systems

Hepzibah A. Christinal

16:10 - 17:10

Student colloquium

 Sunday, 18 October 2009

 

Regular presentation

8:30 ¨C 9:30

Poster:

DNA Algorithm on Making Spanning Tree Problem

Kang Zhou

DNA computing-based cryptography

Xing Wang

A Multilevel Image Encryption Algorithm Based on Chaos and DNA Coding

Qian Wang

An Image Encryption Algorithm Based on DNA Sequence Addition Operation 

Qiang Zhang  

Molecular Beacon-based DNA computing model for Maximum weight clique problem

zhixiang Yin

Programming Problem Based on Sticker Model

Lingying Zhi

9:35-9:55

Overview and Study focuses of microfluidic-based cell culture systems

Manguo Huang

10:00 - 10:20

Three chains of DNA calculate for a category of special integer planning problem

Sheng song Bo

10:20 ¨C 10:40

Morning tea

Session 1

Session chair: Dr. Luca Cardelli, Prof Yin Zhixiang

10:50 - 11:20

Three chains of DNA calculate for a category of

special integer planning problem

Bosheng Song

11:25 - 11:55

DNA Algorithm on Optimal Path Selection for Bus Travel Network

Qian Zhang

12:00 - 12:30

Evolutionary Optimization Programming with Probabilistic Models

Moongu Jeon

12:30 - 13:30

Lunch

13:30 - 14:30

Poster:

Molecular Beacon Based DNA Computing Model for 0-1 Programming Problem

Xiaohui Huang

A position-slots model for nucleosome assembly in the yeast genome based on integrated multi-platform

Jihua Feng

Molecular Computations of the Maximal Clique Problem Using DNA Self-assembly

Jing Yang

Efficient DNA Algorithm for Constructing Ramsey Graph based on Minimal Degree Vertex

Fang Xi

Development of an in vivo computer for 3-SAT Problem

Xiangrong Liu

DNA Computation Model Based on Self-Assembled Nanoparticle Probes for 0-1 Integer Programming Problem

Fei Li

14:30 - 14:50

On the lower bounds of DNA word sets for DNA computing

Bin Wang

14:50 - 15:10

The Research of Codeword Problem in DNA Computing

Hu Juan

15:10 - 15:30

Afternoon tea

15:35 - 15:55

Overview and Study focuses of microfluidic-based cell culture systems
Manguo Huang

16:30 - 17:30

DNA Codewords Design Using the Improved Non-dominated Sorting Genetic Algorithm-II

Yanfeng Wang

17:30 till late

Sunset drinks and conference dinner

Session 2(Evolutionary Computing)

Session chair:  Qiang Zhang

8:30¨C 9:30

Poster:

Classification of 31P MRS for Liver Cancer in vivo

Jun Sang

A Comparative Study of Clustering Algorithms for Protein Sequences

DongMing Tang

Experimental Comparisons of Clonal Selection Algorithms with Different Metadynamics Strategies

Xingxin Pei

Dynamical Model of P53-Mdm2-P14/19ARF Network to Radiation in Population of Cells

Hui Liu

10:50 - 11:20

The Novel Non-linear Strategy of Inertia Weight in Particle Swarm Optimization

Li Li

11:25 - 11:55

Method of Extracting Image Geometric Primitives Based on Immune Algorithm  

ZHI Jun

12:00 - 12:30

A PSO-FUZZY Group Decision-making Support System in Vehicle Performance Evaluation

Li Zhang

12:30 - 13:30

Lunch

13:30 - 14:00

Combining Genetic Algorithm and Random 

Projection Strategy for (l, d)-Motif Discovery

Hongwei Huo

14:05 - 14:35

Theoretical and Empirical Analyses of Evolutionary Negative Selection Algorithms for a Combinational Optimization Problem

Xingxin Pei

14:40 ¨C 15:00

Afternoon tea

15:00 - 15:30

A Novel Approach to HMM-Based Speech Recognition System Using Particle Swarm Optimization

Negin Najkar

15:35 - 16:05

Quantum Swarm Evolutionary Algorithm With Time-Varying Acceleration Coefficients for Partner Selection in Virtual Enterprise

Jianhua Xiao

16:10 - 16:40

An Effective Initialization Strategy of Pheromone for Ant Colony Optimization

Qiguo Dai

16:45 ¨C 17:15

Using the BPSO Algorithm in Image Segmentation for Dynamic Thresholding

L.Djerou

17:30 till late

Sunset drinks and conference dinner

Session 3(Membrane Computing and others)

Session chair: Prof. Gexiang Zhang

8:30¨C 9:30

Poster:

Measurement and evaluation of the material metabolism capability in typical Chinese cities

Yating Li

A study of gaits in Parkinson's patients using Autoregressive Model

Yang Han

Prediction of Interspecies Transmission for Avian Influenza A Virus Based on BP Neural Network

Xiaoli Qiang

Orthogonal Locality Discriminant Embedding for Document Classification

Ziqiang Wang

Spectral Clustering for Detecting Protein Complexes in PPI Networks

Guimin Qin

Partitioning the State Space By Critical States

Zhao Jin

Application of Rough Set and Support Vector Machine in Competency Assessment

Huizhen Liu

9:35-9:55

P Systems and Context-free 2D Picture Languages

K.G. Subramanian

10:00 - 10:20

Pulse Coupled Neural Network Based Anisotropic Diffusion Method for 1/f Noise Reduction

Deng Zhang

10:20 - 10:40

Moring Tea

10:40 - 11:00

Constrained Trajectory Optimization Using Migrant Particle Swarm Optimization Algorithm

Fuqiang Xie

11:05 - 11:25

Generic Object Recognition with Biologically-Inspired Features

Changxin Gao

11:30 - 11:50

Lunch

11:50 - 13:30

A Nonlinear Grade Estimation Method Based on Wavelet Neural Network

LI Xiao-li

13:30 - 14:30

Prediction of Protein-Protein Interaction Types Using the Decision Templates

Wei Chen

14:30 - 14:50

Afternoon tea

14:50 - 15:10

Output Tracking Control of Switched Nonlinear Singular System Using Neural Networks

Xin Chen

15:15 - 15:35

Solving Multidimensional 0¨C1 Knapsack Problem by Tissue P Systems with Cell Division

Juanjuan He

15:40 - 16:00

A Biologically Motivated Corner Detection Method Based on the Oriented Receptive Fields of Simple Cortical Cells

Wanying Xu

16:30 - 17:30

Close

17:30 till late

Sunset drinks and conference dinner

Mon.,19 October 2009

Optional post-conference tour

 
Invited speakers

The invited speakers for BIC-TA 2009 and abstracts of their presentations are given below. You can view the professional biographies of the invited speakers by clicking on their names.

The invited speakers for BIC-TA 2008 and abstracts of their presentations are given below. You can view the professional biographies of the invited speakers by clicking on their names.

Luca Cardelli (Microsoft Research, Cambridge UK))

Title: Molecules as Automata

Abstract:

Chemical and biochemical systems are described as collectives of interacting stochastic automata: each automaton represents a molecule that undergoes state transitions. This framework constitutes an artificial biochemistry, where automata interact by the equivalent of the law of mass action. We analyze systems and networks, both by stochastic and continuous methods, and relate the two approaches. Interacting automata are a computational system inspired by biochemistry, but it is also possible to go the other way, and implement these automata by using DNA technology.

Fumiaki Tanaka (Tokyo University)

Title: DNA as a versatile programming language for nano-engineering

Abstract

DNA is a bio-molecule that contains information in its sequence.

Nowadays, we can design DNA sequences and purchase them at a reasonably low cost.

This enables us to control the hybridization (binding) between DNA molecules with appropriately designed sequences.

Thus, DNA is a useful material for engineering such as nano-fabrication, nano-robotics, molecular computation, and so on.

In fact, many researchers succeeded in the construction of various molecular systems including logic gates and nanostructures by DNA.

In this talk, I will start with the explanation why I regard DNA as a programming language.

Then, I introduce representative molecular systems: DNA enzyme-free logic gates and 2D or 3D DNA nanostructures.

Through these examples, I discuss how to design and implement these molecular systems.  

Zhigong Wang(Southeast University)

Title: Microelectronics-Embedded Channel Bridging and Signal Regeneration of Injured Spinal Cords or among Neuron Assemble

Abstract

Due to the difficulty in the regeneration of injured spinal cord by biological methods, microelectronic neural bridge, which is a new concept based on microelectronic technology, is presented. The microelectronic system has been realized in the forms of hybrid and integrated circuits. The integrated circuits for neural signal detecting, stimulation, and regeneration are realized in a CMOS process. In the animal experiments with 100 toads, 48 rats, and 3 rabbits, nerve signals have been successfully detected from spinal cords and sciatic nerves, and functional electrical stimulation has been carried out for spinal cords and sciatic nerves. When the microelectronic system is bridged between the controlling and stimulated nerve, the relevant motion of legs and nerve signal waveforms, which are stimulated by evoked or spontaneous nerve signal through such system, have been observed. Therefore, the feasibility of the presented method was demonstrated.

In addition, we have developed a microelectrode array (MEA) chip for in-vitro signal stimulating. recording, and bridging of neuron assemble. The chip comprises 14´14 active sensor cells. Each sensor cell is 6mm´6mm in dimension, including a 15mm´25mm stimulating electrode, a 15mm´25mm recording electrode, two NMOS switches which can linearly transfer signals with peak-to-peak values from 50 mV to 500 mV. The chip is realized in a standard 0.5 mm DPDM (double-poly double-metal) CMOS technology and will be used as interface of a neuron assemble and an electronic system.

Junying (Joanna) Zhang (Xidian University)

Title: Substantially Causative Factor Discovery for SNP Association Study based on Association Stability

Abstract:

The ultimate goal of the approach is to identify the substantially causative relations between SNP products and phenotypes, and hence the top priority of this approach is to develop a reverse engineering method that provides significant predictions.

In this approach, SNP association study as a typical biologically initiated data-driven reverse engineering problem, is divided into two phases: substantially causative (SC) factor discovery, referred briefly to as SC-FD, and substantially causative interaction between each SC factor and the trait, referred to as SC model estimation, or briefly SC-ME. The ultimate goal is to understand biological mechanism of phenotypes on SNPs, and to even further interfere in the variants of the SNPs biologically for treatment of disease. Both are of great challenges: no precise definition on the problem yet, no prior knowledge, noisy data, curse of dimensionality, and insensitivity to techniques used (since the substantial cause of a disease does not matter with the techniques used and absolutely classifier independent). It becomes more serious when it is a genome-wide study on both discovering methods and computation expenses. All makes present feature based approaches (e.g., feature selection) not available.

In this approach, a brand new approach for the reverse engineering SC factor discovery is proposed. At first, we make four reasonable conjectures on the SC factors: large association (Conj 1), large stability (Conj 2) and large joint effect (Conj 3), all for one SC factor, and non-overlap between the SC factors (Conj 4). By the light of the conjectures, association, stability and joint effect of a factor are mathematically defined. In addition, discover-and-remove framework for SC factor discovery is given, which includes three consecutive phases: searching a factor pool, gaining candidate SC factors from the factor pool, and selecting a SC factor from the candidate SC factors. The computationally acceptable SC factor discovery (SC-FD) algorithm is proposed which includes three algorithms for the three phases.

The characteristics of SC factors and feasibility of applying and evaluating the performance of our proposed algorithm to the analysis of large numbers of SNPs was investigated primarily via simulation. The data comes from 223 individuals that were genotyped on the 317K Illunina HumanHap300 BeadChip, and processed by biologists to form SNP datasets of different number of SNPs. 100SNPs dataset, 250SNPs dataset, 500SNPs dataset, 1000SNPs dataset, and 2000SNPs dataset, where the number of SNPs is 100, 250, 500, 1000, and 2000 respectively, with 7 ground truth factors of different sizes hidden by biologists in each dataset were used in our experiment. By running the proposed SC-FD algorithm on each of these datasets, 5 or even 6 out of 7 ground truth SC factors were successfully discovered for each dataset. This indicates that the proposed algorithm is very effective in SC factor discovery. Other real dataset experiments were also performed.